Чтобы разместить заголовок в центре DataGridView в VB.NET, вы можете использовать различные методы. Вот несколько подходов, которые вы можете попробовать:

1. Использование DataGridViewCellStyle:

   Dim headerStyle As New DataGridViewCellStyle()
   headerStyle.Alignment = DataGridViewContentAlignment.MiddleCenter
   dataGridView1.ColumnHeadersDefaultCellStyle = headerStyle

2. Настройка события CellPainting:

   Private Sub dataGridView1_CellPainting(sender As Object, e As DataGridViewCellPaintingEventArgs) Handles dataGridView1.CellPainting
   If e.RowIndex = -1 AndAlso e.ColumnIndex > -1 Then
       e.PaintBackground(e.CellBounds, True)
       Dim headerBounds As Rectangle = e.CellBounds
       headerBounds.Inflate(-2, -2)
       e.Graphics.DrawString(e.Value.ToString(), dataGridView1.Font, Brushes.Black, headerBounds, New StringFormat() With {.Alignment = StringAlignment.Center, .LineAlignment = StringAlignment.Center})
       e.Handled = True
   End If
   End Sub

3. Создание собственного стиля ячейки заголовка:

   Public Class CenterHeaderCell
   Inherits DataGridViewColumnHeaderCell
   Protected Overrides Sub Paint(graphics As Graphics, clipBounds As Rectangle, cellBounds As Rectangle, rowIndex As Integer, dataGridViewElementState As DataGridViewElementStates, value As Object, formattedValue As Object, errorText As String, cellStyle As DataGridViewCellStyle, advancedBorderStyle As DataGridViewAdvancedBorderStyle, paintParts As DataGridViewPaintParts)
       MyBase.Paint(graphics, clipBounds, cellBounds, rowIndex, dataGridViewElementState, value, formattedValue, errorText, cellStyle, advancedBorderStyle, paintParts)
   
       Dim headerBounds As Rectangle = cellBounds
       headerBounds.Inflate(-2, -2)
       graphics.DrawString(value.ToString(), cellStyle.Font, Brushes.Black, headerBounds, New StringFormat() With {.Alignment = StringAlignment.Center, .LineAlignment = StringAlignment.Center})
   End Sub
   End Class

   Затем присвойте пользовательский стиль ячейки заголовка нужному столбцу:

   dataGridView1.Columns("ColumnName").HeaderCell = New CenterHeaderCell()

Эти методы помогут вам центрировать заголовок в DataGridView в VB.NET.